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The Science Behind MyBreathPrint

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Early Disease Detection Inspired by Our K9 Companions

With about 220 million scent receptors — humans only have 5 million — dogs can smell things that seem unfathomable to us. Dogs have smell receptors 10,000 times more accurate than humans, which means their nose is powerful enough to detect substances at concentrations of one part per trillion — a single drop of liquid in 20 Olympic-size swimming pools!
Dogs are also known for detecting cancer. They can be trained to sniff out a variety of types, including skin, breast and bladder cancer, using samples from known cancer patients and people without cancer.

What if you could reduce or alleviate the dread, pain, expense, wait and risk of the diagnostic journey by developing a system that can identify disease in the breath, like a dog’s nose can, while also improving outcomes through early detection with regular noninvasive, painless screenings? This question is at the heart of Vocxi’s mission and vision to develop the most approachable, accessible and accurate breath diagnostic, saving millions of lives, one patient at a time. 

What is a volatile organic compound?

VOLATILE ORGANIC COMPOUNDS (VOCs) are gaseous molecules. They can originate either from within the body (endogenous VOCs) through a process called lipid peroxidation or from external sources such as diet, prescription drugs and environmental exposure (exogenous VOCs).  VOCs progress into the bloodstream, filtering through the lungs every minute. Your lungs, very efficient tissue-based filters, expel these VOCs with every exhale.

Diseases have detectable VOC patterns

STUDIES HAVE IDENTIFIED OVER 1,000 VOCs that can be found in human breath. Alongside respiratory droplets, VOCs provide a rich source of information regarding an individual’s health and also have great potential to serve as indicators of disease onset and progression as well as overall health status. Decades of research into VOCs have associated unique complex mixtures of VOC biomarker metabolites with specific diseases.

Multi-VOC patterns can identify health

VOCs CAN BE ANALYZED TO IDENTIFY CHEMICAL elements and patterns to reproduce a combination as unique as a fingerprint…or a BreathPrint®. A BreathPrint pattern can change based on what you eat, what you inhale, etc., but MyBreathPrint® was developed to ignore the noise of your morning coffee breath and focus on your metabolism and potential disease markers. Each disease leaves its distinctive mark on a BreathPrint. 

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How the System Works

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Establishing Your BreathPrint After One Minute of Breathing

About MyBreathPrint
MyBreathPrint is a noninvasive, early disease detection system that delivers accurate results with just one minute of breathing: no needles, no radiation, no waiting. The actual device is no bigger than a deck of cards.
The chemistry
Our team of scientists integrated graphene technology with self-assembled monolayers of chemical receptors to create a nanosensor sensitive enough (detecting at the parts per billion level) to detect VOCs. 
Nanotechnology
MyBreathPrint connects VOCs to diseases through richly comprehensive electrochemical patterns from the breath which are generated from the interaction of the VOCs and the nanosensors.
Machine learning
With leading-edge data science techniques, Vocxi Health can analyze the patterns of thousands of VOCs to generate your unique BreathPrint and ultimately, ascertain your health.  
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how the data travels

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From Your Breath to Your Doctor in Seconds 

The MyBreathPrint system really is this simple to use, with immediate, accurate results delivered in a matter of seconds.

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BREATHE

The patient breathes into the mask attached to the MyBreathPrint device for one minute.

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Cloud

The electrochemical patterns captured by the device’s sensor array are sent instantly through the MyBreathPrint app to the cloud.

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BreathML

The BreathML platform generates a BreathPrint and analyzes whether a patient has a disease/ ailment or does not.

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NOTIFICATION

MyBreathPrint delivers the analysis and patient’s results directly to the physician.

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discuss

The physician meets with the patient to discuss the results and if next steps are necessary.

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patient experience

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BREATHE

Bring the mask to your face, covering your mouth and nose and breathe into the mask for one minute.

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results

Results are being delivered to your physician in a matter of seconds.

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next steps

Your doctor will receive your BreathPrint and can share the results with you immediately!

With its metabolomic approach and machine-learning platform, MyBreathPrint is a highly accurate, accessible, noninvasive disease detector.

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A Breath-through Solution

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Human Breath Intelligence

The breakthrough of MyBreathPrint to detect disease early, immediately and noninvasively is at the intersection of nanotechnology, chemistry and machine learning.

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THE BREATH
SOLUTION

Learn more about why our team of scientists, medical-device and diagnostic leaders developed MyBreathPrint.

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Be a part of the Vocxi mission and help us bring MyBreathPrint to millions of patients worldwide!

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